Revolutionizing Infertility Treatment: New Recombinant Hormones Developed by Vietnam’s Researchers

In the field of reproductive medicine, a major breakthrough has been achieved by Associate Professor Dr. Nguyen Thi Mong Diep and her colleagues at Quy Nhon University. The team has successfully developed two new recombinant gonadotropin hormones, hFSH (human Follicle Stimulating Hormone) and eCG (equine Chorionic Gonadotropin), which offer a more sustainable, cost-effective, and accessible solution for infertility treatment in humans and animals.

The development of these hormones was made possible through funding from Vingroup Innovation Fund (VINIF) for the project “Production of single-chain gonadotropins for fertility treatment.” By April 2024, the team had successfully launched the two hormones, which have been shown to be biologically effective and require only a single injection for the entire treatment process. The production process included design, plasmid amplification, expression on cells, purification, biological activity analysis in the laboratory, and testing on mammalian models.

The use of natural gonadotropin hormones for treating infertility in humans and animals has been common practice for many years. However, challenges such as hygiene and ethical issues make their production and supply problematic. Associate Professor Dr. Nguyen Thi Mong Diep’s research aimed to address these challenges by developing recombinant gonadotropin hormones as a viable alternative. These hormones offer a more sustainable and cost-effective solution for infertility treatment in humans and reproduction control in animals.

The research conducted by Associate Professor Dr. Nguyen Thi Mong Diep’s team has significant commercialization potential and can contribute to advancing Vietnam’s biotechnology sector. The development of single-chain recombinant hormones hFSH and eCG has shown promising results in improving fertility for both humans and animals. This groundbreaking research could revolutionize assisted reproductive techniques by providing a more effective and accessible solution to patients seeking fertility treatment.

Dr. Huynh Gia Bao, an expert in in vitro fertilization (IVF) techniques, is optimistic about the potential impact of this research project on Vietnamese patients who seek affordable access to IVF treatments.

Associate Professor Dr. Nguyen Thi Mong Diep is recognized internationally for her accomplishments in France where she met professor standards in 2024.

Overall, the research conducted by Associate Professor Dr. Nguyen Thi Mong Diep’s team represents a significant advancement in reproductive support technology with the potential to benefit both human and animal fertility.

In conclusion, this new approach to infertility treatment using recombinant single-chain hormones offers hope for couples who are seeking alternative solutions that are more sustainable, cost-effective, and accessible than traditional methods while also being highly effective at supporting the entire reproductive process with just one injection!